Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CPT1A | P50416 | 5/20 | 0.42 |
| ▸ | CPT1B | Q92523 | 5/20 | 0.42 |
| ▸ | SCD | O00767 | 6/20 | 0.42 |
| ▸ | PDE5A | O76074 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070906 | 0.91 | MAPT (0.56) | CYP1A2CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL2667539 | 0.91 | GCK (0.42) | CYP1A2CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL2667655 | 0.89 | CPT1A (0.44) | CPT1ACPT1BSCDPDE5ARAB9A | |
| SCHEMBL9070911 | 0.85 | GCK (0.46) | CYP1A2CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL9070943 | 0.85 | GCK (0.45) | CYP1A2CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL2667481 | 0.84 | F2 (0.42) | CYP1A2CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL2667552 | 0.84 | ALDH1A1 (0.43) | CYP1A2CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL2667980 | 0.84 | GCK (0.47) | MAPTSCDRAB9AMAPK1ALDH1A1 | |
| SCHEMBL2667546 | 0.83 | MAPT (0.52) | CYP1A2CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL9070966 | 0.80 | GRM5 (0.50) | MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |