Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070903 | 0.98 | GCK (0.48) | GCKHRH3 | |
| SCHEMBL9070902 | 0.93 | HRH3 (0.46) | GCKHRH3 | |
| SCHEMBL2667566 | 0.92 | HRH3 (0.43) | GCKHRH3 | |
| SCHEMBL2667693 | 0.88 | GCK (0.47) | GCKMEN1GAAHTTKMT2A | |
| SCHEMBL2667997 | 0.86 | GCK (0.49) | GCKHRH3MEN1GAAHTT | |
| SCHEMBL9071015 | 0.83 | GCK (0.50) | GCKHRH3 | |
| SCHEMBL2667976 | 0.83 | F10 (0.37) | GCK | |
| SCHEMBL9070947 | 0.83 | GCK (0.53) | GCK | |
| SCHEMBL9070942 | 0.81 | GCK (0.49) | GCKHRH3OPRM1 | |
| SCHEMBL2667387 | 0.81 | GCK (0.55) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |