Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 15/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667693 | 0.98 | GCK (0.47) | GCKKCNH2F10PRSS1PRSS2 | |
| SCHEMBL9070952 | 0.92 | MDM2 (0.48) | GCKKCNH2F10PRSS1PRSS2 | |
| SCHEMBL9071057 | 0.89 | GCK (0.53) | GCKKCNH2 | |
| SCHEMBL9070903 | 0.88 | GCK (0.48) | GCKKCNH2HRH3 | |
| SCHEMBL2667970 | 0.87 | GCK (0.51) | GCKKCNH2 | |
| SCHEMBL9070944 | 0.86 | GCK (0.46) | GCKMEN1GAAHTTKMT2A | |
| SCHEMBL2667770 | 0.84 | F2 (0.43) | GCKF10PRSS1PRSS2PRSS3 | |
| SCHEMBL9070832 | 0.82 | F10 (0.43) | GCKF10PRSS1PRSS2PRSS3 | |
| SCHEMBL9070902 | 0.81 | HRH3 (0.46) | GCKKCNH2HRH3 | |
| SCHEMBL2668004 | 0.80 | GCK (0.56) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |