Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.37 |
| ▸ | GCK | P35557 | 12/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070832 | 0.87 | F10 (0.43) | F10GCKF2BRD4 | |
| SCHEMBL9070903 | 0.83 | GCK (0.48) | GCK | |
| SCHEMBL9070944 | 0.83 | GCK (0.46) | GCK | |
| SCHEMBL9070902 | 0.82 | HRH3 (0.46) | GCK | |
| SCHEMBL9070904 | 0.82 | GCK (0.56) | GCKRARARARBRARG | |
| SCHEMBL2667566 | 0.81 | HRH3 (0.43) | GCK | |
| SCHEMBL2667978 | 0.81 | GCK (0.41) | GCKRARARARBRARG | |
| SCHEMBL2667980 | 0.79 | GCK (0.47) | GCKBRD4 | |
| SCHEMBL2667770 | 0.76 | F2 (0.43) | F10GCKF2 | |
| SCHEMBL9070908 | 0.76 | CYP1A2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |