Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.46 |
| ▸ | GCK | P35557 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070944 | 0.93 | GCK (0.46) | HRH3GCK | |
| SCHEMBL9070903 | 0.93 | GCK (0.48) | HRH3GCKKCNH2 | |
| SCHEMBL2667566 | 0.90 | HRH3 (0.43) | HRH3GCKGRM5LRRK2KDM4E | |
| SCHEMBL9071015 | 0.90 | GCK (0.50) | HRH3GCKKCNH2 | |
| SCHEMBL2667475 | 0.83 | GCK (0.51) | HRH3GCK | |
| SCHEMBL2667479 | 0.82 | GCK (0.45) | HRH3GCKGRM5KCNH2LRRK2 | |
| SCHEMBL9070901 | 0.82 | GCK (0.51) | HRH3GCKKCNH2 | |
| SCHEMBL2667976 | 0.82 | F10 (0.37) | GCK | |
| SCHEMBL2667997 | 0.81 | GCK (0.49) | HRH3GCKKCNH2 | |
| SCHEMBL2667693 | 0.81 | GCK (0.47) | GCKKCNH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |