Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | SELE | P16581 | 1/20 | 0.43 |
| ▸ | GCK | P35557 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667693 | 0.92 | GCK (0.47) | GCKKCNH2SCDF10PRSS1 | |
| SCHEMBL2667997 | 0.92 | GCK (0.49) | GCKKCNH2F10PRSS1PRSS2 | |
| SCHEMBL2667566 | 0.89 | HRH3 (0.43) | MDM2GCKHRH3ALDH1A1LRRK2 | |
| SCHEMBL2667727 | 0.85 | ALDH1A1 (0.46) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL9071057 | 0.81 | GCK (0.53) | GCKKCNH2 | |
| SCHEMBL2667970 | 0.81 | GCK (0.51) | GCKKCNH2 | |
| SCHEMBL2667770 | 0.81 | F2 (0.43) | SELEGCKF10PRSS1PRSS2 | |
| SCHEMBL9070949 | 0.81 | GCK (0.66) | MDM2GCKKCNH2SCDKMT2A | |
| SCHEMBL9070903 | 0.80 | GCK (0.48) | GCKKCNH2HRH3 | |
| SCHEMBL9070944 | 0.80 | GCK (0.46) | GCKHRH3KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |