Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883059 | 0.89 | CES2 (0.42) | CES2LMNAKMT2AMEN1FAAH | |
| SCHEMBL2046135 | 0.86 | CES2 (0.38) | CES2LMNAKMT2AMEN1FAAH | |
| SCHEMBL28518752 | 0.77 | CES2 (0.33) | CES2KMT2AMEN1FAAHMAPT | |
| SCHEMBL28458802 | 0.76 | KMT2A (0.42) | CES2LMNAKMT2AMEN1FAAH | |
| SCHEMBL28425590 | 0.73 | DGKA (0.41) | CES2LMNAKMT2AMEN1MAPK1 | |
| SCHEMBL28423523 | 0.73 | DGKA (0.41) | CES2LMNAKMT2AMEN1MAPK1 | |
| SCHEMBL28421163 | 0.73 | DGKA (0.41) | CES2LMNAKMT2AMEN1MAPK1 | |
| SCHEMBL28419913 | 0.73 | DGKA (0.41) | CES2LMNAKMT2AMEN1MAPK1 | |
| SCHEMBL28423583 | 0.73 | DGKA (0.41) | CES2LMNAKMT2AMEN1MAPK1 | |
| SCHEMBL28424605 | 0.73 | DGKA (0.41) | CES2LMNAKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871824-B1 | COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION | BRIDGESTONE CORP (JP) | 2017-03-01 | — | — | EP | disclosed |
| EP-2277939-B1 | Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission | BRIDGESTONE CORP (JP) | 2017-02-22 | — | — | EP | disclosed |
| US-20160347777-A1 | COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION | BRIDGESTONE CORPORATION (JP) | 2016-12-01 | — | — | US | disclosed |
| US-9447244-B2 | Methods of making blocked-mercapto alkoxy-modified silsesquioxane compounds | BRIDGESTONE CORPORATION (JP) | 2016-09-20 | — | — | US | disclosed |
| US-9403969-B2 | Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission | BRIDGESTONE CORPORATION (JP) | 2016-08-02 | — | — | US | disclosed |
| US-20150225506-A1 | METHODS OF MAKING BLOCKED-MERCAPTO ALKOXY-MODIFIED SILSESQUIOXANE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2015-08-13 | — | — | US | disclosed |
| US-8962746-B2 | Methods of making blocked-mercapto alkoxy-modified silsesquioxane compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20140011924-A1 | COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION | BRIDGESTONE CORPORATION (JP) | 2014-01-09 | — | — | US | disclosed |
| US-8288474-B2 | Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission | BRIDGESTONE CORPORATION (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20110180195-A1 | COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION | BRIDGESTONE CORPORATION (JP) | 2011-07-28 | — | — | US | disclosed |
| EP-2277939-A1 | Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission | Bridgestone Corporation (JP) | 2011-01-26 | — | — | EP | disclosed |
| US-7799870-B2 | Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission | BRIDGESTONE CORPORATION (JP) | 2010-09-21 | — | — | US | disclosed |
| US-20090171014-A1 | METHODS OF MAKING BLOCKED-MERCAPTO ALKOXY-MODIFIED SILSESQUIOXANE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |
| EP-1871824-A1 | COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION | Bridgestone Corporation (JP) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006102518-A1 | COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION | BRIDGESTONE CORPORATION (JP) | 2006-09-28 | — | — | WO | disclosed |
| US-20060217473-A1 | Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission | BRIDGESTONE CORPORATION (JP) | 2006-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160347777-A1 | COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION | OR51E2, RIF1, SRMS | CES2 1308/4885LMNA 698/4885KMT2A 2784/4885 |
| US-20060217473-A1 | Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission | OR51E2, RIF1, SRMS | CES2 1308/4885LMNA 698/4885KMT2A 2784/4885 |
| US-20110180195-A1 | COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION | OR51E2, RIF1, SRMS | CES2 1308/4885LMNA 698/4885KMT2A 2784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.