Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9074644 | 0.91 | DRD2 (0.41) | ALDH1A1SMN1; SMN2MAPTMEN1MITF | |
| SCHEMBL9076134 | 0.89 | DRD2 (0.35) | ALDH1A1SMN1; SMN2MAPTMEN1MITF | |
| SCHEMBL9074695 | 0.88 | SIGMAR1 (0.31) | SMN1; SMN2SIGMAR1NPC1RAB9A | |
| SCHEMBL9074929 | 0.88 | SPHK1 (0.36) | CYP19A1BACE1DRD2 | |
| SCHEMBL9073174 | 0.87 | SPHK1 (0.38) | CYP19A1BACE1 | |
| SCHEMBL9074254 | 0.87 | SPHK1 (0.38) | CYP19A1BACE1 | |
| SCHEMBL9075832 | 0.87 | SPHK1 (0.38) | CYP19A1BACE1 | |
| SCHEMBL9073407 | 0.85 | CYP19A1 (0.39) | ALDH1A1SMN1; SMN2MAPTCYP19A1L3MBTL1 | |
| SCHEMBL9073223 | 0.84 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTMEN1MITF | |
| SCHEMBL9075867 | 0.81 | PPARA (0.33) | SIGMAR1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545444-A | Diamino compounds and liquid crystal aligning films | CHISSO CORPORATION (JP) | 1996-08-13 | — | — | US | disclosed |
| US-5430195-A | Diamino compounds and liquid crystal aligning films | CHISSO CORPORATION (JP) | 1995-07-04 | — | — | US | disclosed |
| US-5414126-A | Diamino compounds and liquid crystal aligning films | CHISSO CORPORATION (JP) | 1995-05-09 | — | — | US | disclosed |