Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6255307 | 0.91 | CES2 (0.42) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL6257484 | 0.91 | CES2 (0.42) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL29462568 | 0.87 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL1123351 | 0.87 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL28068778 | 0.87 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL11776999 | 0.87 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL30041531 | 0.87 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL9445402 | 0.87 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL11776994 | 0.87 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL1123690 | 0.85 | CES2 (0.50) | CES2CES1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288474-B2 | Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission | BRIDGESTONE CORPORATION (JP) | 2012-10-16 | — | — | US | claimed |
| US-20110180195-A1 | COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION | BRIDGESTONE CORPORATION (JP) | 2011-07-28 | — | — | US | claimed |
| EP-1871824-A1 | COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION | Bridgestone Corporation (JP) | 2008-01-02 | — | — | EP | claimed |
| WO-2006102518-A1 | COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION | BRIDGESTONE CORPORATION (JP) | 2006-09-28 | — | — | WO | claimed |
| US-20060217473-A1 | Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission | BRIDGESTONE CORPORATION (JP) | 2006-09-28 | — | — | US | claimed |
| EP-1995267-B1 | Method for making alkoxy-modified silsesquioxanes | BRIDGESTONE CORP (JP) | 2015-09-09 | — | — | EP | disclosed |
| US-8822620-B2 | Method for making alkoxy-modified silsesquioxanes | BRIDGESTONE CORPORATION (JP) | 2014-09-02 | — | — | US | disclosed |
| US-8501895-B2 | Method for making alkoxy-modified silsesquioxanes and amino alkoxy-modified silsesquioxanes | BRIDGESTONE CORPORATION (JP) | 2013-08-06 | — | — | US | disclosed |
| US-20110144235-A1 | Method For Making Alkoxy-Modified Silsesquioxanes | BRIDGESTONE CORPORATION (JP) | 2011-06-16 | — | — | US | disclosed |
| US-7915368-B2 | Method for making alkoxy-modified silsesquioxanes | BRIDGESTONE CORPORATION (JP) | 2011-03-29 | — | — | US | disclosed |
| EP-2277939-A1 | Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission | Bridgestone Corporation (JP) | 2011-01-26 | — | — | EP | disclosed |
| US-20090326255-A1 | METHOD FOR MAKING ALKOXY-MODIFIED SILSESQUIOXANES AND AMINO ALKOXY-MODIFIED SILSESQUIOXANES | BRIDGESTONE CORPORATION (JP) | 2009-12-31 | — | — | US | disclosed |
| US-7510670-B2 | Free flowing filler composition based on organofunctional silane | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-20080293858-A1 | METHOD FOR MAKING ALKOXY-MODIFIED SILSESQUIOXANES | BRIDGESTONE CORPORATION (JP) | 2008-11-27 | — | — | US | disclosed |
| EP-1995267-A2 | Method for making alkoxy-modified silsesquioxanes | Bridgestone Corporation (JP) | 2008-11-26 | — | — | EP | disclosed |
| US-20070228322-A1 | Free flowing filler composition based on organofunctional silane | MOMENTIVE PERFORMANCE MATERIALS INC. | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326255-A1 | METHOD FOR MAKING ALKOXY-MODIFIED SILSESQUIOXANES AND AMINO ALKOXY-MODIFIED SILSESQUIOXANES | SRMS, ASNS, ACMSD | CES2 254/4885CES1 492/4885GPR84 949/4885 |
| US-20080293858-A1 | METHOD FOR MAKING ALKOXY-MODIFIED SILSESQUIOXANES | STS, SRMS, LSS | CES2 523/4885CES1 435/4885GPR84 524/4885 |
| US-20060217473-A1 | Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission | OR51E2, RIF1, SRMS | CES2 1308/4885CES1 1944/4885GPR84 373/4885 |
| US-20110180195-A1 | COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION | OR51E2, RIF1, SRMS | CES2 1308/4885CES1 1944/4885GPR84 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.