Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17131550 | 0.89 | HPGD (0.53) | HPGDALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL909499 | 0.84 | HPGD (0.60) | HPGDALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL7471764 | 0.82 | HPGD (0.55) | HPGDALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL16465461 | 0.82 | NPC1 (0.52) | HPGDALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL20577869 | 0.82 | HPGD (0.58) | HPGDALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL6912718 | 0.82 | ALDH1A1 (0.60) | HPGDALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL17131554 | 0.81 | HPGD (0.57) | HPGDALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL7355817 | 0.79 | MTNR1A (0.64) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL28198919 | 0.79 | KDM4E (0.60) | HPGDALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL787870 | 0.79 | PKM (0.62) | HPGDALDH1A1SMN1; SMN2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868714-B2 | Pyrone compounds and herbicides comprising the same | SUMITOMO CHEMICAL COMPANY (JP) | 2018-01-16 | — | — | US | disclosed |
| US-9758502-B2 | Dihydropyrone compounds and herbicides comprising the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-09-12 | — | — | US | disclosed |
| EP-2133099-B1 | Conjugated biological molecules and their preparation | POLYTHERICS LTD (GB) | 2017-04-19 | — | — | EP | disclosed |
| US-9439974-B2 | Conjugated biological molecules and their preparation | POLYTHERICS LIMITED (GB) | 2016-09-13 | — | — | US | disclosed |
| US-20150299156-A1 | DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20150274691-A1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2015-10-01 | — | — | US | disclosed |
| EP-2253330-B1 | Conjugated biological molecules and their preparation | POLYTHERICS LTD (GB) | 2015-08-19 | — | — | EP | disclosed |
| EP-2277550-B1 | Process for the preparation of conjugated biological molecules. | POLYTHERICS LTD (GB) | 2015-04-29 | — | — | EP | disclosed |
| US-20140369960-A1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | ABZENA (CAMBRIDGE) LIMITED (GB) | 2014-12-18 | — | — | US | disclosed |
| US-8816051-B2 | Conjugated biological molecules and their preparation | POLYTHERICS LIMITED (GB) | 2014-08-26 | — | — | US | disclosed |
| US-7939630-B2 | Conjugated biological molecules and their preparation | POLYTHERICS LIMITED (GB) | 2011-05-10 | — | — | US | disclosed |
| EP-2277550-A1 | Conjugated biological molecules and their preparation | Polytherics Limited (GB) | 2011-01-26 | — | — | EP | disclosed |
| EP-2253330-A2 | Conjugated biological molecules and their preparation | Polytherics Limited (GB) | 2010-11-24 | — | — | EP | disclosed |
| EP-2133099-A2 | Conjugated biological molecules and their preparation | Polytherics Limited (GB) | 2009-12-16 | — | — | EP | disclosed |
| US-20090298154-A1 | Conjugated biological molecules and their preparation | POLYTHERICS LIMITED (GB) | 2009-12-03 | — | — | US | disclosed |
| US-7595292-B2 | Conjugated biological molecules and their preparation | POLYTHERICS LIMITED (GB) | 2009-09-29 | — | — | US | disclosed |
| EP-1648518-B1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | POLYTHERICS LTD (GB) | 2009-08-26 | — | — | EP | disclosed |
| US-20060210526-A1 | polyoxyethylene glycol-protein conjugate linked via linking group | ABZENA (CAMBRIDGE) LIMITED (GB) | 2006-09-21 | — | — | US | disclosed |
| EP-1648518-A2 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | Polytherics Limited (GB) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005007197-A2 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | POLYTHERICS LIMITED (GB) | 2005-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299156-A1 | DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | CBR3, DDT, WEE2 | HPGD 814/4885ALDH1A1 463/4885SMN1; SMN2 3481/4885 |
| US-20150274691-A1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | CBR3, NOTUM, DDT | HPGD 1690/4885ALDH1A1 1109/4885SMN1; SMN2 3001/4885 |
| US-20140369960-A1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | F13B, F13A1, ZYX | HPGD 958/4885ALDH1A1 3197/4885SMN1; SMN2 4256/4885 |
| US-20090298154-A1 | Conjugated biological molecules and their preparation | F13B, ZYX, F13A1 | HPGD 873/4885ALDH1A1 3013/4885SMN1; SMN2 4291/4885 |
| US-20060210526-A1 | polyoxyethylene glycol-protein conjugate linked via linking group | F13A1, F13B, SSB | HPGD 1287/4885ALDH1A1 4140/4885SMN1; SMN2 3526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.