Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4229752 | 0.83 | MAPT (0.49) | MAPTMEN1KMT2ACNR2GRM5 | |
| SCHEMBL8545034 | 0.82 | HCAR3 (0.51) | HCAR3MAPTMEN1KMT2ALMNA | |
| SCHEMBL152586 | 0.82 | HCAR3 (0.51) | HCAR3MAPTMEN1KMT2ALMNA | |
| SCHEMBL28056250 | 0.82 | HCAR3 (0.51) | HCAR3MAPTMEN1KMT2ALMNA | |
| SCHEMBL7450801 | 0.81 | HCAR3 (0.59) | HCAR3MAPTMEN1KMT2ALMNA | |
| SCHEMBL5422215 | 0.78 | HDAC6 (0.53) | MAPTMEN1KMT2AJAK3IRAK4 | |
| SCHEMBL2343345 | 0.76 | TSHR (0.38) | MEN1KMT2ALMNARAB9ATSHR | |
| SCHEMBL11078454 | 0.74 | ALDH1A1 (0.62) | MAPTMEN1KMT2ALMNATDP1 | |
| SCHEMBL2664557 | 0.73 | HCAR3 (0.65) | HCAR3MAPTMEN1KMT2ARAB9A | |
| SCHEMBL9076114 | 0.73 | HCAR3 (0.43) | HCAR3MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519037-A | N-cyanoamidine derivatives as anti-influenza agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-05-21 | — | — | US | disclosed |
| US-5475012-A | Antiviral against influenza A | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-12-12 | — | — | US | disclosed |
| US-5380734-A | N-cyanoamidine derivatives as anti-influenza agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-01-10 | — | — | US | disclosed |