Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | GRK5 | P34947 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2784147 | 0.70 | NPC1 (0.51) | NPC1LMNARAB9ASMN1; SMN2HTR1A | |
| SCHEMBL10658365 | 0.68 | CES1 (0.51) | NPC1HTR1AGAA | |
| SCHEMBL6269163 | 0.67 | LMNA (0.66) | NPC1LMNARAB9ASMN1; SMN2MAOA | |
| SCHEMBL2784276 | 0.67 | POLB (0.41) | LMNAHTR1AHSD17B3TSHRGSK3A | |
| SCHEMBL2230439 | 0.66 | MAOA (0.48) | NPC1LMNARAB9ASMN1; SMN2MAOA | |
| SCHEMBL5940959 | 0.66 | MAOB (0.64) | NPC1LMNARAB9ASMN1; SMN2MAOA | |
| SCHEMBL10075481 | 0.66 | BRD4 (0.46) | MAOAMAOBHSD17B3TSHRGAA | |
| SCHEMBL3626606 | 0.66 | HSD11B1 (0.45) | NPC1RAB9AHTR1ATSHR | |
| SCHEMBL9827478 | 0.66 | CES1 (0.42) | LMNAHTR1AMAOAMAOBHTR6 | |
| SCHEMBL2767899 | 0.66 | TSHR (0.45) | NPC1LMNARAB9ASMN1; SMN2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488046-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1996-01-30 | — | — | US | disclosed |