Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.58 |
| ▸ | TACR1 | P25103 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 4/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28141917 | 1.00 | CTRB1 (0.58) | CTRB1TACR1CTSLCTSBCTSS | |
| SCHEMBL10430099 | 0.83 | CTSL (0.57) | CTRB1CTSLCTSBCTSSCTSK | |
| SCHEMBL14927646 | 0.82 | CTRB1 (0.61) | CTRB1TACR1CTSLCTSBCTSS | |
| SCHEMBL23501482 | 0.81 | ATM (0.56) | CTRB1CTSLCTSBCTSSCTSK | |
| SCHEMBL13017006 | 0.81 | ATM (0.56) | CTRB1CTSLCTSBCTSSCTSK | |
| SCHEMBL28614288 | 0.81 | ATM (0.44) | CTRB1CTSLCTSSCTSKTRPM8 | |
| SCHEMBL8198203 | 0.80 | CTRB1 (0.58) | CTRB1TACR1CTSLCTSBCTSS | |
| SCHEMBL8198038 | 0.80 | CTRB1 (0.58) | CTRB1TACR1CTSLCTSBCTSS | |
| SCHEMBL10953605 | 0.79 | CTRB1 (0.64) | CTRB1TACR1CTSLCTSBCTSS | |
| SCHEMBL14625712 | 0.79 | CTRB1 (0.64) | CTRB1TACR1CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500414-A | TREATMENT OF PERIODONTAL DISESASE, INHIBITION OF ZINC METALLOPROTEASES | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1996-03-19 | — | — | US | disclosed |
| EP-0249445-A2 | Substituted aminoalkanoylaminoalkyl phosphonate angiotensin converting enzyme inhibitors | E.R. Squibb & Sons, Inc. (US) | 1987-12-16 | — | — | EP | disclosed |