Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 6/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 6/20 | 0.51 |
| ▸ | CTSL | P07711 | 5/20 | 0.51 |
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13017006 | 1.00 | ATM (0.56) | ATMCTSKCTRB1ELANENPC1 | |
| SCHEMBL7372298 | 0.84 | ATM (0.61) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL9074306 | 0.81 | CTRB1 (0.58) | ATMCTSKCTRB1NPC1RAB9A | |
| SCHEMBL28141917 | 0.81 | CTRB1 (0.58) | ATMCTSKCTRB1NPC1RAB9A | |
| SCHEMBL8041576 | 0.81 | ATM (0.64) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL308291 | 0.81 | ATM (0.64) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL9114401 | 0.81 | ALDH1A1 (0.57) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL22808751 | 0.80 | ATM (0.62) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL2059541 | 0.80 | ATM (0.62) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL11094221 | 0.80 | ATM (0.62) | ATMCTSKCTRB1ELANECTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787171-B | Industrial preparation method of compound | 智腾大中华区有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-114787171-A | Industrial process for the preparation of the disodium salt of ((2S) -3- ([1, 1' -biphenyl ] -4-yl) -2- ((hydroxy ((1R) -1- (((1- (isobutyroyloxy) ethoxy) carbonyl) amino) ethyl) phosphoryl) methyl) propionyl) -L-alanine | 领先药物公司 | 2022-07-22 | — | — | CN | disclosed |
| WO-2021116617-A1 | PROCESS FOR INDUSTRIAL PREPARATION OF THE DISODIUM SALT OF ((2S)-3-([1,1'-BIPHENYL]-4-YL)-2-((HYDROXY((1R)-1-(((1-(ISOBUTYRYLOXY)ETHOXY)CARBONYL)AMINO)ETHYL)PHOSPHORYL)METHYL)PROPANOYL)-L-ALANINE | PHARMALEADS (FR) | 2021-06-17 | — | — | WO | disclosed |