SCHEMBL9075368

SCHEMBL9075368

Cc1cccc(C2CCC(c3ccc(Oc4ccc(N)cc4C)c(C)c3)(c3ccc(Oc4ccc(N)cc4C)c(C)c3)CC2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 3/20 0.40
BACE1 P56817 2/20 0.33
DPP4 P27487 1/20 0.33
PPARA Q07869 1/20 0.33
ATP1A1 P05023 2/20 0.33
ATP1B1 P05026 2/20 0.33
ATP1A3 P13637 2/20 0.33
ATP1B2 P14415 2/20 0.33
ATP1A2 P50993 2/20 0.33
ATP1B3 P54709 2/20 0.33
FXYD2 P54710 2/20 0.33
ATP1A4 Q13733 2/20 0.33
ALDH1A1 P00352 1/20 0.33
DRD2 P14416 1/20 0.32
DRD1 P21728 1/20 0.32
DRD4 P21917 1/20 0.32
DRD5 P21918 1/20 0.32
DRD3 P35462 1/20 0.32
HTR2A P28223 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9074907 0.91 ALDH1A1 (0.39) HTR2CBACE1DPP4ATP1A1ATP1B1
SCHEMBL9075958 0.90 PPARA (0.35) PPARAALDH1A1ESR1ESR2
SCHEMBL9075867 0.87 PPARA (0.33) BACE1DPP4PPARA
SCHEMBL9074613 0.85 DRD2 (0.38) BACE1PPARADRD2DRD1DRD4
SCHEMBL9075456 0.84 DRD2 (0.33) PPARADRD2DRD1DRD4DRD5
SCHEMBL9075475 0.83 SPHK1 (0.33) PPARADRD2DRD1DRD4DRD5
SCHEMBL9074805 0.82 SPHK1 (0.35)
SCHEMBL9073206 0.82 SPHK1 (0.35)
SCHEMBL9074327 0.82 SPHK1 (0.35)
SCHEMBL9073223 0.81 ALDH1A1 (0.51) HTR2CATP1A1ATP1B1ATP1A3ATP1B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5545444-A Diamino compounds and liquid crystal aligning films CHISSO CORPORATION (JP) 1996-08-13 US disclosed
US-5430195-A Diamino compounds and liquid crystal aligning films CHISSO CORPORATION (JP) 1995-07-04 US disclosed
US-5414126-A Diamino compounds and liquid crystal aligning films CHISSO CORPORATION (JP) 1995-05-09 US disclosed