SCHEMBL9074907

SCHEMBL9074907

Cc1cccc(C2CCC(c3ccc(Oc4ccc(N)cc4C)cc3)(c3ccc(Oc4ccc(N)cc4C)cc3)CC2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
HTR2C P28335 2/20 0.39
OPRK1 P41145 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GAA P10253 1/20 0.33
DPP4 P27487 1/20 0.32
ATP1A1 P05023 1/20 0.32
ATP1B1 P05026 1/20 0.32
ATP1A3 P13637 1/20 0.32
ATP1B2 P14415 1/20 0.32
ATP1A2 P50993 1/20 0.32
ATP1B3 P54709 1/20 0.32
FXYD2 P54710 1/20 0.32
ATP1A4 Q13733 1/20 0.32
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
BACE1 P56817 2/20 0.31
DRD2 P14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9075368 0.91 HTR2C (0.40) ALDH1A1HTR2CDPP4ATP1A1ATP1B1
SCHEMBL9073190 0.90 SLC6A2 (0.38) ALDH1A1L3MBTL1SLC6A2SLC6A4SLC6A3
SCHEMBL9073223 0.89 ALDH1A1 (0.51) ALDH1A1HTR2CL3MBTL1GAAATP1A1
SCHEMBL9074468 0.88 TEAD4 (0.38) ALDH1A1HTR2CL3MBTL1SLC6A2SLC6A4
SCHEMBL9074695 0.88 SIGMAR1 (0.31) SLC6A2SLC6A4SLC6A3SMN1; SMN2
SCHEMBL9075289 0.86 DRD2 (0.37) SLC6A2SLC6A4SLC6A3BACE1DRD2
SCHEMBL9073213 0.84 BACE1 (0.32) BACE1DRD2DRD1DRD4DRD5
SCHEMBL9074180 0.83 BACE1 (0.33) BACE1
SCHEMBL9075442 0.83 NCOA1 (0.38) ALDH1A1GAASLC6A2SLC6A4SLC6A3
SCHEMBL9075380 0.83 SPHK1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5545444-A Diamino compounds and liquid crystal aligning films CHISSO CORPORATION (JP) 1996-08-13 US disclosed
US-5430195-A Diamino compounds and liquid crystal aligning films CHISSO CORPORATION (JP) 1995-07-04 US disclosed
US-5414126-A Diamino compounds and liquid crystal aligning films CHISSO CORPORATION (JP) 1995-05-09 US disclosed