Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17882028 | 0.94 | LPL (0.43) | MAOBTAAR1LPLLIPGPLK1 | |
| SCHEMBL9074940 | 0.89 | RARB (0.50) | MAOBPLK1NISCHHRH3NPC1 | |
| SCHEMBL9074966 | 0.87 | RARB (0.51) | LPLLIPGHRH3MAPTRAB9A | |
| SCHEMBL9809579 | 0.86 | MAOB (0.63) | MAOBTAAR1FDFT1KIF11 | |
| SCHEMBL9075799 | 0.85 | HSD17B10 (0.54) | LPLLIPGHRH3MAPTRAB9A | |
| SCHEMBL9074699 | 0.85 | HSD17B10 (0.54) | LPLLIPGHRH3MAPTRAB9A | |
| SCHEMBL9075420 | 0.85 | HSD17B10 (0.54) | LPLLIPGHRH3MAPTRAB9A | |
| SCHEMBL8990753 | 0.84 | MAOB (0.61) | MAOBTAAR1FDFT1KIF11 | |
| SCHEMBL9074271 | 0.83 | MAOB (0.41) | MAOBTAAR1NPC1RAB9AKIF11 | |
| SCHEMBL21322216 | 0.82 | CA2 (0.47) | TAAR1LPLLIPGPLK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465621-B1 | PARTIALLY FLUORINATED COMPOUNDS | MERCK PATENT GMBH (DE) | 1996-11-13 | — | — | EP | disclosed |
| WO-1991011418-A1 | PARTIALLY FLUORINATED COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-08-08 | — | — | WO | disclosed |