Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 8/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.36 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11932056 | 0.93 | TP53 (0.42) | NPC1CYP1A2CYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL1687449 | 0.84 | MAOB (0.57) | MAOBKIF11TAAR1 | |
| SCHEMBL9075469 | 0.83 | MAOB (0.47) | MAOBNPC1RAB9AKIF11TAAR1 | |
| SCHEMBL24594088 | 0.83 | MAOB (0.41) | MAOBNPC1CYP1A2CYP2C19RAB9A | |
| SCHEMBL18643754 | 0.82 | KIF11 (0.52) | NPC1RAB9AKIF11EGFRTP53 | |
| SCHEMBL9074940 | 0.80 | RARB (0.50) | MAOBNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL13974830 | 0.80 | EGFR (0.44) | NPC1CYP1A2CYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL8430356 | 0.79 | TP53 (0.42) | NPC1CYP1A2CYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL8990814 | 0.79 | MAOB (0.61) | MAOBKIF11TAAR1 | |
| SCHEMBL9074966 | 0.79 | RARB (0.51) | RAB9ASMN1; SMN2EGFRTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233889-B1 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | SHANGHAI MICURX PHARMACEUTICAL CO LTD (CN) | 2022-07-06 | — | — | EP | disclosed |
| CN-109704914-A | A kind of facile syntheesis new method of 1,1- bis-fluoro ethyls aromatic compound | 山东理工大学 | 2019-05-03 | — | — | CN | disclosed |
| US-9771394-B2 | Antimicrobial polymyxins for treatment of bacterial infections | MICURX PHARMACEUTICALS, INC. (KY) | 2017-09-26 | — | — | US | disclosed |
| US-20160185823-A1 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. | 2016-06-30 | — | — | US | disclosed |
| EP-0465621-B1 | PARTIALLY FLUORINATED COMPOUNDS | MERCK PATENT GMBH (DE) | 1996-11-13 | — | — | EP | disclosed |
| WO-1991011418-A1 | PARTIALLY FLUORINATED COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185823-A1 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | VIP, AQP1, PEF1 | MAOB 3655/4885NPC1 1223/4885CYP1A2 4501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.