Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.67 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.38 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15451466 | 0.90 | TGFBR1 (0.69) | TGFBR1FOLH1NAALAD2RIMKLAKDM4E | |
| SCHEMBL6156710 | 0.84 | TGFBR1 (0.61) | TGFBR1FOLH1ALOX15ALDH1A1LMNA | |
| SCHEMBL6156715 | 0.84 | TGFBR1 (0.61) | TGFBR1FOLH1ALOX15ALDH1A1LMNA | |
| SCHEMBL5331603 | 0.80 | TGFBR1 (1.00) | TGFBR1FOLH1NAALAD2KDM4EMAPT | |
| SCHEMBL4442415 | 0.80 | TGFBR1 (0.71) | TGFBR1FOLH1NAALAD2KDM4EMAPT | |
| SCHEMBL5891585 | 0.80 | TGFBR1 (1.00) | TGFBR1FOLH1NAALAD2KDM4EMAPT | |
| SCHEMBL6658481 | 0.79 | MAPT (0.59) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| SCHEMBL13921443 | 0.79 | MAPT (0.59) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| SCHEMBL4952983 | 0.79 | MAPT (0.59) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| SCHEMBL1556930 | 0.79 | TGFBR1 (0.65) | TGFBR1FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576949-B1 | Optically active amino acid sulphoxide and sulphone derivatives, their preparation, their polymerisation and use as adsorbents for chromatograpic separation of racemates | BAYER AG (DE) | 1996-01-31 | — | — | EP | disclosed |
| US-5481026-A | ADDITION POLYMERIZABLE TO CHROMATOGRAPHIC SUPPORTS FOR SEPARATION OF RACEMIC MIXTURES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-02 | — | — | US | disclosed |
| US-5357001-A | Optically active amino acid sulphoxide and amino acid sulphone derivatives, their preparation, their polymerisation and use as adsorbents for chromatographic resolution of racemates | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-18 | — | — | US | disclosed |
| EP-0576949-A1 | Optically active amino acid sulphoxide and sulphone derivatives, their preparation, their polymerisation and use as adsorbents for chromatograpic separation of racemates | BAYER AG (DE) | 1994-01-05 | — | — | EP | disclosed |