Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156710 | 1.00 | TGFBR1 (0.61) | TGFBR1LMNAALDH1A1NPSR1FOLH1 | |
| SCHEMBL8375419 | 0.85 | TGFBR1 (0.46) | TGFBR1LMNAALDH1A1CA2CA1 | |
| SCHEMBL8936061 | 0.85 | LMNA (0.49) | TGFBR1LMNAALDH1A1NPSR1FOLH1 | |
| SCHEMBL9075541 | 0.84 | TGFBR1 (0.67) | TGFBR1LMNAALDH1A1FOLH1ALOX15 | |
| SCHEMBL109681 | 0.82 | LMNA (0.55) | LMNAALDH1A1NPSR1FOLH1CA2 | |
| SCHEMBL109682 | 0.82 | LMNA (0.55) | LMNAALDH1A1NPSR1FOLH1CA2 | |
| SCHEMBL109680 | 0.82 | LMNA (0.55) | LMNAALDH1A1NPSR1FOLH1CA2 | |
| SCHEMBL1332039 | 0.82 | LMNA (0.55) | LMNAALDH1A1NPSR1FOLH1CA2 | |
| SCHEMBL15451466 | 0.82 | TGFBR1 (0.69) | TGFBR1ALDH1A1FOLH1ALOX15 | |
| SCHEMBL8185993 | 0.80 | TGFBR1 (0.67) | TGFBR1ALDH1A1FOLH1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050165136-A1 | Glass-ionomer cements containing amino acids | UAB RESEARCH FOUNDATION (US) | 2005-07-28 | — | — | US | claimed |
| EP-1503717-A1 | GLASS-IONOMER CEMENTS CONTAINING AMINO ACIDS | The UAB Research Foundation (US) | 2005-02-09 | — | — | EP | claimed |
| WO-2003061606-A1 | GLASS-IONOMER CEMENTS CONTAINING AMINO ACIDS | UAB RESEARCH FOUNDATION (US) | 2003-07-31 | — | — | WO | claimed |
| JP-9227629-A | — | — | None | — | — | JP | disclosed |
| US-20050165136-A1 | Glass-ionomer cements containing amino acids | UAB RESEARCH FOUNDATION (US) | 2005-07-28 | — | — | US | disclosed |
| EP-1503717-A1 | GLASS-IONOMER CEMENTS CONTAINING AMINO ACIDS | The UAB Research Foundation (US) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003061606-A1 | GLASS-IONOMER CEMENTS CONTAINING AMINO ACIDS | UAB RESEARCH FOUNDATION (US) | 2003-07-31 | — | — | WO | disclosed |
| US-6046289-A | FOR INHIBITING COAGULATION OF BLOOD PLATELETS, INHIBITING ADHESION OF ANIMAL CELLS, OR AS SUBSTRATE FOR CULTURING ANIMAL CELLS | FUJIFILM CORPORATION (JP) | 2000-04-04 | — | — | US | disclosed |
| JP-H09227629-A | METHACRYLOYLMETHIONINE POLYMER | NIPPON SODA CO LTD | 1997-09-02 | — | — | JP | disclosed |
| US-5587279-A | HIGH CONCENTRATION OF SILVER CHLORIDE GRAINS | FUJI PHOTO FILM CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0488258-B1 | Propenamide derivatives, polymers, copolymers and use thereof | FUJI PHOTO FILM CO LTD (JP) | 1996-04-17 | — | — | EP | disclosed |
| EP-0488258-A2 | Propenamide derivatives, polymers, copolymers and use thereof | FUJI PHOTO FILM CO., LTD. (JP) | 1992-06-03 | — | — | EP | disclosed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |