Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 3/20 | 0.33 |
| ▸ | METAP1 | P53582 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948095 | 0.86 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10MAPTCRHBP | |
| SCHEMBL9076416 | 0.82 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10MAPTCRHBP | |
| SCHEMBL10073238 | 0.79 | ALDH1A1 (0.32) | ALDH1A1LMNAHSD17B10MAPTCRHBP | |
| SCHEMBL4047581 | 0.78 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10MAPTCRHBP | |
| SCHEMBL8141833 | 0.78 | MAPT (0.34) | ALDH1A1LMNAHSD17B10MAPTCRHBP | |
| SCHEMBL1009673 | 0.77 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10MAPTCRHBP | |
| SCHEMBL15198769 | 0.76 | METAP2 (0.36) | ALDH1A1LMNAHSD17B10MAPTCRHBP | |
| SCHEMBL27911520 | 0.75 | CPA1 (0.31) | MAPTCRHBPCRHR2CPA1 | |
| Potassium Ion SCHEMBL9416725 | 0.75 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10MAPTCRHBP | |
| SCHEMBL9416726 | 0.75 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10MAPTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1033391-C | betaarboline derivatives and process for preparing same and use in pharmaceuticals | SCHERING AG (DE) | 1996-11-27 | — | — | CN | disclosed |
| US-5506234-A | PSYCHOPHARMACEUTICAL AGENTS WHICH BIND TO BENZODIAZEPINE RECEPTORS; ANXIOLYTIC AGENTS; MINIMAL SIDE EFFECTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-04-09 | — | — | US | disclosed |
| CN-1070403-A | New-beta-carboline derivatives and preparation and medicinal application | SCHERING AG (DE) | 1993-03-31 | — | — | CN | disclosed |
| US-4757070-A | 3-oxadiazolyl-5-aminoalkyl-beta-carboline derivatives compositions and use | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-07-12 | — | — | US | disclosed |
| US-4731365-A | 5-aminoalkyl-beta-carboline derivatives, psycho tropic compositions and use | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-03-15 | — | — | US | disclosed |
| US-4433162-A | REACTING FATTY ACID VINYL ESTER WITH A NITROGEN OXIDE IN PRESENCE OF OXYGEN, THEN ALCOHOLYSIS | UBE INDUSTRIES, LTD. (JP) | 1984-02-21 | — | — | US | disclosed |