Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9075640 | 0.86 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10MAPTCRHBP | |
| SCHEMBL9076416 | 0.80 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10MAPTCRHBP | |
| SCHEMBL4047581 | 0.80 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10MAPTCRHBP | |
| SCHEMBL29145008 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1009673 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10MAPTCRHBP | |
| SCHEMBL10073238 | 0.77 | ALDH1A1 (0.32) | ALDH1A1LMNAHSD17B10MAPTCRHBP | |
| SCHEMBL27911520 | 0.77 | CPA1 (0.31) | MAPTCRHBPCRHR2CPA1 | |
| SCHEMBL9416726 | 0.77 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10MAPTCRHBP | |
| SCHEMBL29145004 | 0.77 | TSHR (0.37) | — | |
| Potassium Ion SCHEMBL9416725 | 0.77 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10MAPTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105968-A | Method for selectively synthesizing carboglycoside by using nitroalkane compound as sugar receptor | 三峡大学 | 2023-11-24 | — | — | CN | claimed |
| CN-117105968-A | Method for selectively synthesizing carboglycoside by using nitroalkane compound as sugar receptor | 三峡大学 | 2023-11-24 | — | — | CN | disclosed |
| EP-3862354-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2021-08-11 | — | — | EP | disclosed |
| EP-2824105-B1 | Indolopyridines as Eg5 kinesin modulators | 4SC AG (DE) | 2021-03-31 | — | — | EP | disclosed |
| EP-2824105-A1 | Indolopyridines as Eg5 kinesin modulators | 4SC AG (DE) | 2015-01-14 | — | — | EP | disclosed |
| US-8530493-B2 | Indolopyridines as Eg5 kinesin modulators | 4SC AG (DE) | 2013-09-10 | — | — | US | disclosed |
| US-20090246169-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | NYCOMED GMBH (DE) | 2009-10-01 | — | — | US | disclosed |
| US-20090233902-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2009-09-17 | — | — | US | disclosed |
| EP-2033962-A1 | Tetracyclic indolopyridines as EG5 inhibitors | 4SC AG (DE) | 2009-03-11 | — | — | EP | disclosed |
| WO-2009024613-A1 | TETRACYCLIC INDOLOPYRIDINES AS EG5 INHIBITORS | 4SC AG (DE) | 2009-02-26 | — | — | WO | disclosed |
| EP-1996592-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | Nycomed GmbH (DE) | 2008-12-03 | — | — | EP | disclosed |
| EP-1994033-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007096393-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007096395-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233902-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | KIF5A, KIF5C, KIF5B | ALDH1A1 2483/4885LMNA 3053/4885HSD17B10 3171/4885 |
| US-20090246169-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | KIF5A, KIF5C, KIF5B | ALDH1A1 2483/4885LMNA 3053/4885HSD17B10 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.