Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.61 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 3/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475993 | 0.81 | ESR1 (0.75) | ESR1ESR2LTA4HHRH3 | |
| SCHEMBL1359959 | 0.80 | ESR1 (0.76) | ESR1ESR2LTA4HHRH3 | |
| SCHEMBL699174 | 0.80 | ESR1 (0.76) | ESR1ESR2LTA4HHRH3 | |
| SCHEMBL7436764 | 0.79 | LTA4H (0.71) | ESR1ESR2LTA4HHRH3BACE1 | |
| SCHEMBL13649149 | 0.78 | ESR1 (0.70) | ESR1ESR2LTA4HHRH3 | |
| SCHEMBL14767389 | 0.76 | ESR1 (0.60) | ESR1ESR2LTA4HHRH3 | |
| SCHEMBL14767387 | 0.76 | ESR1 (0.63) | ESR1ESR2LTA4HHRH3 | |
| SCHEMBL5649675 | 0.75 | PSMB1 (0.82) | ESR1ESR2LTA4HHRH3 | |
| SCHEMBL4688676 | 0.73 | HRH3 (0.72) | ESR1ESR2HRH3 | |
| SCHEMBL7458270 | 0.73 | ESR1 (0.68) | ESR1ESR2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512684-A | Process for preparing 3-(4-aminoethoxy-benzoyl) benzo B!-thiophenes | ELI LILLY AND COMPANY (US) | 1996-04-30 | — | — | US | disclosed |