⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL907574 | 1.00 | — | — | |
| SCHEMBL12646872 | 1.00 | — | — | |
| SCHEMBL11959881 | 0.83 | — | — | |
| SCHEMBL12817327 | 0.83 | — | — | |
| SCHEMBL5873964 | 0.81 | FAAH (0.50) | — | |
| SCHEMBL5873961 | 0.81 | FAAH (0.50) | — | |
| SCHEMBL5873963 | 0.81 | FAAH (0.50) | — | |
| SCHEMBL1059082 | 0.80 | — | — | |
| SCHEMBL1059084 | 0.80 | — | — | |
| SCHEMBL7814020 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10934531-B2 | Method for enantioselective carbene C—H insertion using an iron-containing protein catalyst | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2021-03-02 | — | — | US | disclosed |
| US-10934531-B2 | Method for enantioselective carbene C—H insertion using an iron-containing protein catalyst | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2021-03-02 | — | — | US | disclosed |
| EP-3142499-B1 | HOMOVANILLIC ACID ESTERS, IN PARTICULAR FOR ACHIEVING AN IMPRESSION OF HEAT AND/OR SPICINESS | SYMRISE AG (DE) | 2019-10-30 | — | — | EP | disclosed |
| US-20190276805-A1 | METHOD FOR ENANTIOSELECTIVE CARBENE C-H INSERTION USING AN IRON-CONTAINING PROTEIN CATALYST | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-09-12 | — | — | US | disclosed |
| US-20190276805-A1 | METHOD FOR ENANTIOSELECTIVE CARBENE C-H INSERTION USING AN IRON-CONTAINING PROTEIN CATALYST | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-09-12 | — | — | US | disclosed |
| WO-2017162284-A1 | HOMOVANILLIC ACID ESTER FOR REDUCING OR INHIBITING FATTY ACID ABSORPTION IN THE SMALL INTESTINE | SYMRISE AG (DE) | 2017-09-28 | — | — | WO | disclosed |
| CN-102015670-B | Method for producing vinyl ether compound | KURARAY CO | 2013-06-19 | — | — | CN | disclosed |
| US-8318952-B2 | Substituted indole derivatives for the treatment of respiratory diseases | ONO PHARMACEUTICAL CO., LTD. (JP) | 2012-11-27 | — | — | US | disclosed |
| EP-2487149-A1 | METHOD FOR PRODUCING KETONE | JX Nippon Oil & Energy Corporation (JP) | 2012-08-15 | — | — | EP | disclosed |
| US-20120197036-A1 | METHOD FOR MANUFACTURING KETONE | OSAKA UNIVERSITY (JP) | 2012-08-02 | — | — | US | disclosed |
| EP-2277871-A1 | METHOD FOR PRODUCING VINYL ETHER COMPOUND | Kuraray Co., Ltd. (JP) | 2011-01-26 | — | — | EP | disclosed |
| US-20100234368-A1 | CONDENSED RING COMPOUND AND USE THEREOF | TAKEUCHI JUN | 2010-09-16 | — | — | US | disclosed |
| US-7763610-B2 | Carboxylic acid derived benzoxazines as agents for the treatment of respiratory diseases | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-07-27 | — | — | US | disclosed |
| EP-2084255-A1 | FRAGRANCE COMPOSITIONS | Givaudan Nederland Services B.V. (NL) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008050086-A1 | FRAGRANCE COMPOSITIONS | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2008-05-02 | — | — | WO | disclosed |
| US-5004568-A | Reacting With Carbon Monoxide Using A Group 8 Noble Metal Halide Catalyst And A Group 1B Metal Halide | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1991-04-02 | — | — | US | disclosed |
| US-4767574-A | CATALYTIC WITH GROUP 8 NOBLE METAL HALIDE AND HALIDE COMPOUND | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1988-08-30 | — | — | US | disclosed |
| US-4675435-A | CARBONYLATION OF ACYCLIC ALLYLIC ETHER | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1987-06-23 | — | — | US | disclosed |
| EP-0217407-A2 | Carbonylation of allylic ethers to esters | QUANTUM CHEMICAL CORPORATION (a Virginia corp.) (US) | 1987-04-08 | — | — | EP | disclosed |
| US-4622416-A | GROUP 8 HALIDE CATALYSTS | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1986-11-11 | — | — | US | disclosed |