SCHEMBL5873964

SCHEMBL5873964

CCCCCC=CCOC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.50
TRPV1 Q8NER1 2/20 0.50
LPAR3 Q9UBY5 1/20 0.44
TERT O14746 3/20 0.43
MAPT P10636 2/20 0.43
BLM P54132 2/20 0.43
HSD17B10 Q99714 2/20 0.43
FABP4 P15090 2/20 0.43
PTPN1 P18031 2/20 0.43
PPARG P37231 2/20 0.43
PPARD Q03181 2/20 0.43
PPARA Q07869 2/20 0.43
GMNN O75496 1/20 0.43
USP2 O75604 1/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
POLB P06746 1/20 0.43
CYP2C9 P11712 1/20 0.43
ALOX15 P16050 1/20 0.43
APEX1 P27695 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5873963 1.00 FAAH (0.50) FAAHTRPV1LPAR3TERTMAPT
SCHEMBL5873961 1.00 FAAH (0.50) FAAHTRPV1LPAR3TERTMAPT
SCHEMBL12648890 0.98 FAAH (0.54) FAAHTRPV1LPAR3TERTMAPT
SCHEMBL11959870 0.98 FAAH (0.54) FAAHTRPV1LPAR3TERTMAPT
SCHEMBL10998659 0.98 FAAH (0.54) FAAHTRPV1LPAR3TERTMAPT
SCHEMBL25272849 0.98 FAAH (0.54) FAAHTRPV1LPAR3TERTMAPT
SCHEMBL10998662 0.98 FAAH (0.54) FAAHTRPV1LPAR3TERTMAPT
SCHEMBL6696768 0.98 FAAH (0.54) FAAHTRPV1LPAR3TERTMAPT
SCHEMBL12817327 0.92
SCHEMBL11959881 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2487149-A1 METHOD FOR PRODUCING KETONE JX Nippon Oil & Energy Corporation (JP) 2012-08-15 EP disclosed
US-20120197036-A1 METHOD FOR MANUFACTURING KETONE OSAKA UNIVERSITY (JP) 2012-08-02 US disclosed
US-7030286-B2 Reacting 1,3-butadiene with a telogen such as methanol, using a telomerization catalyst to form a telomer, partially hydrogenating the telomer to form a 1-substituted 2-octene and dissociating it to give 1-octene OXENO OLEFINCHEMIE GMBH (DE) 2006-04-18 US disclosed
EP-1358140-B1 METHOD FOR PRODUCING 1-OCTEN OXENO OLEFINCHEMIE GMBH (DE) 2004-12-29 EP disclosed
US-20040059170-A1 Method for producing 1-octen OXENO OLEFINCHEMIE GMBH (DE) 2004-03-25 US disclosed
EP-1358140-A1 METHOD FOR PRODUCING 1-OCTEN Oxeno Olefinchemie GmbH (DE) 2003-11-05 EP disclosed
WO-2002062732-A1 METHOD FOR PRODUCING 1-OCTEN OXENO OLEFINCHEMIE GMBH (DE) 2002-08-15 WO disclosed
US-4135045-A PROCESS FOR POLYMERIZATION OF OLEFINS AND CATALYST COMPOSITION THEREFOR MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1979-01-16 US disclosed
US-4048415-A TITANIUM-ALUMINUM COORDINATION CATALYSTS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1977-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040059170-A1 Method for producing 1-octen TELO2, DOHH, TPH2 FAAH 135/4885TRPV1 3407/4885LPAR3 3337/4885
US-20120197036-A1 METHOD FOR MANUFACTURING KETONE CBR1, CBR3, DUOX1 FAAH 998/4885TRPV1 4553/4885LPAR3 3562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.