Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653337 | 0.93 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8658459 | 0.88 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8653340 | 0.87 | DRD2 (0.52) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL21750486 | 0.81 | KDM4E (0.70) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL21750481 | 0.79 | KMT2A (0.70) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7760294 | 0.78 | KDM4E (0.61) | KDM4EALDH1A1SMN1; SMN2LMNADRD2 | |
| SCHEMBL21750484 | 0.76 | ALDH1A1 (0.70) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15040819 | 0.74 | KDM4E (0.62) | KDM4EALDH1A1LMNA | |
| SCHEMBL21750478 | 0.74 | KDM4E (0.67) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11806695 | 0.74 | DRD2 (0.51) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512684-A | Process for preparing 3-(4-aminoethoxy-benzoyl) benzo B!-thiophenes | ELI LILLY AND COMPANY (US) | 1996-04-30 | — | — | US | disclosed |