Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9076474 | 1.00 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| Iodide SCHEMBL8906768 | 0.98 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| Iodide SCHEMBL8907661 | 0.92 | HCAR2 (0.44) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| Iodide SCHEMBL8906995 | 0.90 | HCAR2 (0.43) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL31681514 | 0.85 | HCAR2 (0.55) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL5023381 | 0.81 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL1879680 | 0.81 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL1583861 | 0.81 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL9527552 | 0.81 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL264932 | 0.81 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597095-B1 | PROSTAGLANDIN E1 ANALOGUE | TAISHO PHARMACEUTICAL CO LTD (JP) | 1996-10-30 | — | — | EP | disclosed |