Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8841212 | 0.89 | ALDH1A1 (0.46) | MAPTTP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9075646 | 0.70 | SMN1; SMN2 (0.45) | MAPTTP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8554644 | 0.70 | ALDH1A1 (0.40) | MAPTNPC1RAB9ASMN1; SMN2THRB | |
| SCHEMBL9074252 | 0.70 | MAOB (0.50) | TP53NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11231792 | 0.70 | SNCA (0.45) | POLB | |
| SCHEMBL8307015 | 0.69 | KDM4E (0.46) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL11234379 | 0.68 | ACHE (0.48) | MAPTTP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11239564 | 0.68 | CA12 (0.58) | MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8305401 | 0.67 | CA12 (0.53) | MAPTTP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9613267 | 0.67 | NPC1 (0.64) | MAPTNPC1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565488-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | claimed |