Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9076806 | 0.86 | MAOB (0.42) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL8305401 | 0.83 | CA12 (0.53) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL8841216 | 0.83 | HIF1A (0.44) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL8841210 | 0.81 | MAPT (0.51) | SMN1; SMN2ALDH1A1HPGDKDM4ERAB9A | |
| SCHEMBL9074052 | 0.81 | HIF1A (0.47) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL8326230 | 0.77 | CYP19A1 (0.44) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL9074252 | 0.76 | MAOB (0.50) | SMN1; SMN2ALDH1A1NPC1RAB9AGAA | |
| SCHEMBL11224072 | 0.75 | ALDH1A1 (0.77) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL10557875 | 0.74 | MAPT (0.75) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL9076541 | 0.70 | MAPT (0.44) | SMN1; SMN2NPC1RAB9AMAPTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565488-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | claimed |