Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 14/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 13/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9077490 | 0.91 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9076323 | 0.87 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL9076710 | 0.82 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9078933 | 0.81 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL9078095 | 0.77 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9076237 | 0.77 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL991961 | 0.73 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL992501 | 0.73 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9076714 | 0.73 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9076344 | 0.73 | AGTR1 (0.57) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527815-A | TREATMENT OF HYPERTENSION, CONGESTIVE HEART FAILURE, AND HIGH INTRAOCULAR PRESSURE | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1996-06-18 | — | — | US | disclosed |