SCHEMBL991961

SCHEMBL991961

CCCc1nc(C(C)(C)O)c(C(=O)OCC)n1Cc1ccc(-c2ccccc2-c2nnn(C(c3ccccc3)(c3ccccc3)c3ccccc3)n2)cc1

nearest known ligand 0.69

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 6/20 0.59
AGTR2 P50052 6/20 0.59
ABCC3 O15438 1/20 0.56
ABCC4 O15439 1/20 0.56
ABCB11 O95342 1/20 0.56
CYP3A4 P08684 1/20 0.56
PDE4D Q08499 1/20 0.56
PDE3A Q14432 1/20 0.56
SLCO1B3 Q9NPD5 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
SLCO1B1 Q9Y6L6 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28484414 0.94 AGTR1 (0.59) AGTR1AGTR2ABCC3ABCC4ABCB11
SCHEMBL6595211 0.94 AGTR1 (0.52) AGTR1AGTR2ABCC3ABCC4ABCB11
SCHEMBL991977 0.92 AGTR1 (0.69) AGTR1AGTR2ABCC3ABCC4ABCB11
SCHEMBL1275437 0.92 AGTR1 (0.55) AGTR1AGTR2ABCC3ABCC4ABCB11
Potassium Ion SCHEMBL16872384 0.90 AGTR1 (0.60) AGTR1AGTR2ABCC3ABCC4ABCB11
SCHEMBL992501 0.89 AGTR1 (0.51) AGTR1AGTR2ABCC3ABCC4ABCB11
SCHEMBL94332 0.89 AGTR1 (0.74) AGTR1AGTR2ABCC3ABCC4ABCB11
SCHEMBL9259068 0.89 AGTR1 (0.52) AGTR1AGTR2ABCC3ABCC4ABCB11
SCHEMBL16872178 0.89 AGTR1 (0.62) AGTR1AGTR2ABCC3ABCC4ABCB11
SCHEMBL1966071 0.87 AGTR1 (0.59) AGTR1AGTR2ABCC3ABCC4ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011007368-A2 AN IMPROVED PROCESS FOR PREPARATION OF OLMESARTAN CADILA HEALTHCARE LIMITED (IN) 2011-01-20 WO claimed
EP-1916246-A2 An improved process for the preparation of olmesartan medoxomil Cadila Pharmaceuticals Limited (IN) 2008-04-30 EP claimed
CN-118255753-A Synthesis method of olmesartan medoxomil intermediate 黄冈鲁班药业股份有限公司 2024-06-28 CN disclosed
EP-2891650-B1 METHOD FOR PRODUCING BIARYL COMPOUND API CORP (JP) 2018-08-01 EP disclosed
US-9624181-B2 Method for producing biaryl compound API CORPORATION (JP) 2017-04-18 US disclosed
US-20150239853-A1 METHOD FOR PRODUCING BIARYL COMPOUND API CORPORATION (JP) 2015-08-27 US disclosed
EP-2891650-A1 METHOD FOR PRODUCING BIARYL COMPOUND API Corporation (JP) 2015-07-08 EP disclosed
WO-2011007368-A3 AN IMPROVED PROCESS FOR PREPARATION OF OLMESARTAN CADILA HEALTHCARE LIMITED (IN) 2011-07-21 WO disclosed
WO-2011036674-A1 A NEW PROCESS FOR THE PREPARATION OF OLMESARTAN MEDOXOMIL INOGENT LABORATORIES PRIVATE LIMITED (IN) 2011-03-31 WO disclosed
WO-2011014611-A2 PREPARATION OF OLMESARTAN MEDOXOMIL DR. REDDY'S LABORATORIES LTD. (IN) 2011-02-03 WO disclosed
WO-2011007368-A2 AN IMPROVED PROCESS FOR PREPARATION OF OLMESARTAN CADILA HEALTHCARE LIMITED (IN) 2011-01-20 WO disclosed
WO-2011007368-A2 AN IMPROVED PROCESS FOR PREPARATION OF OLMESARTAN CADILA HEALTHCARE LIMITED (IN) 2011-01-20 WO disclosed
US-20090069397-A1 DEUTERIUM-ENRICHED OLMESARTAN PROTIA, LLC (US) 2009-03-12 US disclosed
US-20090069397-A1 DEUTERIUM-ENRICHED OLMESARTAN PROTIA, LLC (US) 2009-03-12 US disclosed
EP-1916246-A3 An improved process for the preparation of olmesartan medoxomil Cadila Pharmaceuticals Limited (IN) 2008-06-18 EP disclosed
EP-1916246-A2 An improved process for the preparation of olmesartan medoxomil Cadila Pharmaceuticals Limited (IN) 2008-04-30 EP disclosed
EP-1916246-A2 An improved process for the preparation of olmesartan medoxomil Cadila Pharmaceuticals Limited (IN) 2008-04-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150239853-A1 METHOD FOR PRODUCING BIARYL COMPOUND MLX, BMX, BRIX1 AGTR1 1993/4885AGTR2 954/4885ABCC3 1950/4885
US-20090069397-A1 DEUTERIUM-ENRICHED OLMESARTAN REN, NR3C2, AVPR2 AGTR1 4/4885AGTR2 6/4885ABCC3 3663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.