Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 5/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9551288 | 0.86 | ALDH1A1 (0.49) | KCNN4KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9551373 | 0.79 | KDM4E (0.45) | KDM4EALDH1A1HPGDHTTMAPT | |
| SCHEMBL9573993 | 0.78 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDHTTMAPT | |
| SCHEMBL9078473 | 0.78 | MEN1 (0.54) | KDM4EALDH1A1HPGD | |
| SCHEMBL8586424 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1HPGDHTTMAPT | |
| SCHEMBL9301532 | 0.73 | MEN1 (0.40) | KCNN4KDM4EALDH1A1HTTMAPT | |
| SCHEMBL9280327 | 0.72 | GAA (0.49) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL8840237 | 0.68 | TTR (0.43) | PIM1PIM3KDM4EALDH1A1NPC1 | |
| SCHEMBL9528669 | 0.67 | MAPT (0.35) | KDM4EALDH1A1HPGDHTTMAPT | |
| SCHEMBL10561176 | 0.67 | ALDH1A1 (0.40) | ALDH1A1HTTCA5ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8239370-A | — | — | None | — | — | JP | disclosed |
| JP-H08239370-A | 2-(2-(2,6-DIFLUOROPHENYL)-1,3,4-THIADIAZOL-5-YL-OXY)-ACETAMIDE | BAYER AG | 1996-09-17 | — | — | JP | disclosed |