Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 6/20 | 0.38 |
| ▸ | IDH1 | O75874 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9074668 | 0.78 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2TSHRHTT | |
| SCHEMBL8436037 | 0.78 | IDH1 (0.38) | NPC1RAB9ASMN1; SMN2TSHRHTT | |
| SCHEMBL8438550 | 0.78 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2TSHRHTT | |
| SCHEMBL9077297 | 0.77 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2TSHRHTT | |
| SCHEMBL9231746 | 0.76 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2TSHRHTT | |
| SCHEMBL8438552 | 0.75 | SMN1; SMN2 (0.42) | NPC1RAB9ASMN1; SMN2TSHRHTT | |
| SCHEMBL8435003 | 0.70 | RAB9A (0.35) | NPC1RAB9ASMN1; SMN2TSHRHTT | |
| SCHEMBL9076104 | 0.69 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2TSHRHTT | |
| SCHEMBL9593626 | 0.64 | HTT (0.56) | NPC1RAB9ASMN1; SMN2TSHRHTT | |
| SCHEMBL20320576 | 0.64 | HTT (0.35) | SMN1; SMN2TSHRHTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543416-A | Cyanoisoxazoles | BASF AKTIENGESELLSCHAFT (DE) | 1996-08-06 | — | — | US | disclosed |