Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 7/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9231746 | 0.80 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9ATSHRHTT | |
| SCHEMBL8438550 | 0.80 | NPC1 (0.45) | SMN1; SMN2NPC1RAB9ATSHRHTT | |
| SCHEMBL9205495 | 0.79 | SMN1; SMN2 (0.36) | SMN1; SMN2NPC1RAB9ATSHRHTT | |
| SCHEMBL9201897 | 0.78 | PRKAB2 (0.32) | SMN1; SMN2GABRA5 | |
| SCHEMBL8986729 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9ATSHRHTT | |
| SCHEMBL9077785 | 0.75 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9ATSHRHTT | |
| SCHEMBL9077297 | 0.74 | NPC1 (0.42) | SMN1; SMN2NPC1RAB9ATSHRHTT | |
| SCHEMBL9198518 | 0.70 | LMNA (0.36) | SMN1; SMN2NPC1RAB9ATSHRHTT | |
| SCHEMBL8435003 | 0.69 | RAB9A (0.35) | SMN1; SMN2NPC1RAB9ATSHRHTT | |
| SCHEMBL9196921 | 0.68 | HTT (0.37) | SMN1; SMN2NPC1RAB9ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669326-B1 | Cyanoisoxazoles | BASF AG (DE) | 1999-12-22 | — | — | EP | disclosed |
| EP-0669326-A1 | Cyanoisoxazoles | BASF Aktiengesellschaft (DE) | 1995-08-30 | — | — | EP | disclosed |