SCHEMBL9078971

SCHEMBL9078971

CCCCCC([Si](Cl)(Cl)CC(C)c1ccccc1CC)[Si](Cl)(Cl)CC(C)c1ccccc1CC

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 7/20 0.36
CYSLTR1 Q9Y271 7/20 0.36
ALDH1A1 P00352 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CNR2 P34972 1/20 0.31
PPARG P37231 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9079635 0.84 ESR1 (0.32) MEN1KMT2ANPSR1
SCHEMBL6682255 0.80 CYSLTR2 (0.43) CYSLTR2CYSLTR1ALDH1A1MEN1KMT2A
SCHEMBL9081432 0.80 AOC3 (0.39) ALDH1A1
SCHEMBL6679577 0.79 CYSLTR2 (0.46) CYSLTR2CYSLTR1ALDH1A1MEN1KMT2A
SCHEMBL5488086 0.77 TSHR (0.37) ALDH1A1NPSR1
SCHEMBL6682017 0.75 CYSLTR2 (0.41) CYSLTR2CYSLTR1ALDH1A1NPSR1CNR2
SCHEMBL9722014 0.71 TSHR (0.41) CYSLTR2CYSLTR1NPSR1
SCHEMBL9080668 0.69
SCHEMBL9078908 0.69
SCHEMBL17027746 0.68 CYSLTR2 (0.41) CYSLTR2CYSLTR1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5527934-A HYDROSILATING BIS(DICHLOROSILYL)METHANES WITH ORGANOOLEFINS OR ORGANOSILYLOLEFINS IN THE PRESENCE OF CHLOROPLATINIC ACID CATALYST KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1996-06-18 US disclosed