Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013455 | 0.91 | PDE4D (0.60) | PDE4DADORA3POLBNPSR1ALDH1A1 | |
| SCHEMBL6013476 | 0.84 | ADORA1 (0.56) | PDE4DADORA3POLBNPSR1ALDH1A1 | |
| SCHEMBL7516958 | 0.82 | PDE4D (0.45) | PDE4DADORA3POLBNPSR1ALDH1A1 | |
| SCHEMBL8313649 | 0.79 | ALDH1A1 (0.47) | PDE4DADORA3POLBNPSR1ALDH1A1 | |
| SCHEMBL8315668 | 0.77 | ALDH1A1 (0.46) | PDE4DADORA3POLBNPSR1ALDH1A1 | |
| SCHEMBL8315473 | 0.76 | ALDH1A1 (0.48) | NPSR1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL24442196 | 0.75 | GABRP (0.45) | NPSR1ALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL10435451 | 0.75 | GABRP (0.45) | NPSR1ALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL8311271 | 0.75 | KMT2A (0.48) | NPSR1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL7510715 | 0.74 | PDE4D (0.45) | PDE4DADORA3POLBNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492906-A | ANTIASTHMATICS, ANTIALLERGENS, GASTROINTESTINAL PROTECTORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1996-02-20 | — | — | US | disclosed |