Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19358952 | 0.83 | SRC (0.41) | SRCCYP2D6LMNAMAPK1KMT2A | |
| SCHEMBL19358950 | 0.80 | LMNA (0.47) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL2580805 | 0.74 | MEN1 (0.47) | SRCKMT2A | |
| SCHEMBL2237165 | 0.71 | DPP4 (0.42) | CES2CES1CTSD | |
| SCHEMBL23343751 | 0.70 | RIPK1 (0.41) | SRCCYP2D6LMNAKMT2AL3MBTL1 | |
| SCHEMBL2043473 | 0.69 | — | — | |
| SCHEMBL16854173 | 0.69 | TSHR (0.38) | TDP1 | |
| SCHEMBL11775055 | 0.69 | SRC (0.50) | SRCCYP2D6LMNAMAPK1KMT2A | |
| SCHEMBL22863330 | 0.69 | SRC (0.56) | SRCCYP2D6LMNAMAPK1KMT2A | |
| SCHEMBL28428 | 0.69 | SRC (0.56) | SRCCYP2D6LMNAMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550263-A | PHOSPHOLIPID TO WHICH X-RAY CONTRAST AGENT HAS BEEN COVALENTLY LINKED BY ESTER OR AMIDE BOND | KARLSHAMNS LIPIDTEKNIK AB (SE) | 1996-08-27 | — | — | US | claimed |