Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 6/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.54 |
| ▸ | RNF4 | P78317 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081600 | 0.86 | RNF4 (0.53) | STAT3NR3C1LTB4R2RNF4CNR2 | |
| SCHEMBL9081184 | 0.81 | NR3C1 (0.49) | STAT3NR3C1PTGESPOLBSRD5A2 | |
| SCHEMBL9079799 | 0.78 | POLB (0.51) | STAT3NR3C1PTGESPOLBSRD5A2 | |
| SCHEMBL9081335 | 0.78 | STAT3 (0.49) | STAT3NR3C1PTGESPOLB | |
| SCHEMBL17076869 | 0.78 | STAT3 (0.86) | STAT3PTGESALOX5 | |
| SCHEMBL9080906 | 0.77 | LPAR1 (0.58) | STAT3PTGESPOLB | |
| SCHEMBL9080531 | 0.76 | TSHR (0.55) | STAT3NR3C1 | |
| SCHEMBL9081215 | 0.76 | TSHR (0.55) | STAT3NR3C1 | |
| SCHEMBL9080371 | 0.76 | TSHR (0.55) | STAT3NR3C1 | |
| SCHEMBL9081721 | 0.76 | TSHR (0.55) | STAT3NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |