SCHEMBL9080260

SCHEMBL9080260

Cc1nc(-c2ccc(F)cc2)nc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
ADORA3 P0DMS8 2/20 0.35
ADORA2A P29274 2/20 0.35
DPP4 P27487 1/20 0.35
KCNH2 Q12809 1/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.33
HRH4 Q9H3N8 1/20 0.33
APP P05067 1/20 0.33
DHPS P49366 1/20 0.33
PTGS2 P35354 1/20 0.33
CHRNA7 P36544 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
DYRK1A Q13627 1/20 0.33
ADORA1 P30542 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL126470 0.87 RAB9A (0.37) NPC1RAB9ASMN1; SMN2ADORA3ADORA2A
SCHEMBL11941643 0.84 NPC1 (0.44) L3MBTL1NPC1RAB9ASMN1; SMN2ADORA3
SCHEMBL9081785 0.83 LMNA (0.47) L3MBTL1NPC1RAB9AADORA3DPP4
SCHEMBL9079576 0.82 L3MBTL1 (0.64) L3MBTL1NPC1RAB9ASMN1; SMN2ADORA3
SCHEMBL24840512 0.81 L3MBTL1 (0.60) L3MBTL1NPC1RAB9ASMN1; SMN2ADORA3
SCHEMBL28827833 0.81 L3MBTL1 (0.54) L3MBTL1NPC1RAB9ASMN1; SMN2ADORA3
SCHEMBL18344442 0.81 KDM4E (0.39) NPC1RAB9ASMN1; SMN2ADORA3ADORA2A
SCHEMBL9081804 0.80 CHRNA7 (0.48) L3MBTL1NPC1RAB9ASMN1; SMN2ADORA3
SCHEMBL27100735 0.80 TP53 (0.39) L3MBTL1NPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL9081795 0.79 GAA (0.40) L3MBTL1HRH4KDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489499-A DISCOLORATION INHIBITION, STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1996-02-06 US disclosed