Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5243244 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2GAAHSD17B10 | |
| SCHEMBL370253 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2GAAHSD17B10 | |
| SCHEMBL11358203 | 0.78 | GABRR1 (0.39) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL1186099 | 0.71 | KDM4E (0.68) | KDM4EALDH1A1SMN1; SMN2GAAHSD17B10 | |
| SCHEMBL7762855 | 0.71 | PDE4D (0.45) | KDM4EALDH1A1LMNASOAT1KMT2A | |
| SCHEMBL6677747 | 0.70 | ALDH1A1 (0.41) | KDM4EALDH1A1SMN1; SMN2GAAHSD17B10 | |
| SCHEMBL9236366 | 0.70 | ALDH1A1 (0.41) | KDM4EALDH1A1SMN1; SMN2GAAHSD17B10 | |
| SCHEMBL9542969 | 0.70 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2GAAHSD17B10 | |
| SCHEMBL4605821 | 0.69 | ALDH1A1 (0.40) | KDM4EALDH1A1SMN1; SMN2GAAHSD17B10 | |
| SCHEMBL2565429 | 0.69 | ALDH1A1 (0.40) | KDM4EALDH1A1SMN1; SMN2HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996007645-A1 | NEW PROCESS FOR PREPARING 1-PHENYL-IMIDAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-03-14 | — | — | WO | disclosed |