SCHEMBL9236366

SCHEMBL9236366

CCOC(=O)Oc1[nH]nnc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
PDE4D Q08499 1/20 0.40
SOAT1 P35610 1/20 0.39
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
KMT2A Q03164 3/20 0.33
KDM4E B2RXH2 3/20 0.33
LMNA P02545 3/20 0.33
MEN1 O00255 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
POLB P06746 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CACNA1F O60840 2/20 0.32
CACNA1D Q01668 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10655346 0.85 ELANE (0.38) ALDH1A1LMNACYP1A2CYP2C19SMN1; SMN2
SCHEMBL28537481 0.80 ACHE (0.35) PDE4DCA12CA1CA2CA9
SCHEMBL7762855 0.76 PDE4D (0.45) ALDH1A1PDE4DSOAT1CA12CA1
SCHEMBL28527246 0.71 THRB (0.37) ALDH1A1HSD17B10TP53TSHR
SCHEMBL9272935 0.70 PDE4D (0.50) ALDH1A1PDE4DCA12CA1CA2
SCHEMBL9080422 0.70 KDM4E (0.44) ALDH1A1SOAT1KMT2AKDM4ELMNA
SCHEMBL7760150 0.68 ALDH1A1 (0.35) ALDH1A1PDE4DSOAT1CYP1A2CYP2C19
SCHEMBL5243244 0.67 KDM4E (0.44) ALDH1A1SOAT1KMT2AKDM4ELMNA
SCHEMBL7973627 0.66 ALDH1A1 (0.48) ALDH1A1SOAT1CA12CA1CA2
SCHEMBL1577573 0.66 ALDH1A1 (0.43) ALDH1A1PDE4DSOAT1CA2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648761-A2 Quinazolinyl yellow coupler for photographic recording material Agfa-Gevaert AG (DE) 1995-04-19 EP disclosed