Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5243244 | 0.88 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2GAAHSD17B10 | |
| SCHEMBL9080422 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2GAAHSD17B10 | |
| SCHEMBL9542969 | 0.78 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2GAAHSD17B10 | |
| SCHEMBL9540477 | 0.75 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2GAAHSD17B10 | |
| SCHEMBL9540494 | 0.75 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2GAAHSD17B10 | |
| SCHEMBL2114938 | 0.73 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2GAAHSD17B10 | |
| SCHEMBL6677747 | 0.71 | ALDH1A1 (0.41) | KDM4EALDH1A1SMN1; SMN2GAAHSD17B10 | |
| SCHEMBL4605821 | 0.70 | ALDH1A1 (0.40) | KDM4EALDH1A1SMN1; SMN2GAAHSD17B10 | |
| SCHEMBL10438826 | 0.70 | ALDH1A1 (0.40) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL2565429 | 0.70 | ALDH1A1 (0.40) | KDM4EALDH1A1SMN1; SMN2HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593447-A2 | NEW HETEROCYCLIC COMPOUNDS AS PESTICIDES | Bayer Intellectual Property GmbH (DE) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007500-A2 | NEW HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-19 | — | — | WO | disclosed |