Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.47 |
| ▸ | VEGFA | P15692 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9350788 | 0.79 | HTT (1.00) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL3496060 | 0.75 | NOTUM (0.64) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL4257630 | 0.73 | ADORA2A (0.44) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL22868176 | 0.73 | HTT (0.84) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL4265207 | 0.72 | NOTUM (0.48) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL4273292 | 0.70 | NOTUM (0.52) | KDM4EMEN1KMT2APOLBNOTUM | |
| SCHEMBL17111036 | 0.69 | HTR6 (0.55) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL29696630 | 0.69 | HTR6 (0.55) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL9877955 | 0.69 | HDAC8 (0.49) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL4315216 | 0.69 | CYP2D6 (0.47) | HTTSMN1; SMN2KDM4ETP53CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552551-A | COLORS FOR PHOSPHORESCENCE | FLORIDA STATE UNIVERSITY (US) | 1996-09-03 | — | — | US | claimed |
| US-5552551-A | COLORS FOR PHOSPHORESCENCE | FLORIDA STATE UNIVERSITY (US) | 1996-09-03 | — | — | US | disclosed |