Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | COMT | P21964 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM6A | O15550 | 1/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22868176 | 0.91 | HTT (0.84) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL28783695 | 0.84 | SMN1; SMN2 (0.72) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| Hydrochloric Acid SCHEMBL30701773 | 0.83 | SMN1; SMN2 (0.70) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL13485866 | 0.80 | MMP2 (0.83) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL9080467 | 0.79 | HTT (0.65) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL20382962 | 0.77 | HTT (0.62) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL5525055 | 0.77 | KDM4E (0.62) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL16479459 | 0.76 | NOTUM (0.62) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL15660704 | 0.76 | KDM4E (0.60) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL3083137 | 0.76 | KDM4E (0.61) | HTTSMN1; SMN2KDM4ETP53CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614378-A1 | TECHNETIUM-99 m COMPLEXES WITH N-SUBSTITUTED 3-HYDROXY-4-PYRIDINONES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-09-14 | — | — | EP | disclosed |
| US-5336482-A | Diagnostic scintigraphic imaging | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-08-09 | — | — | US | disclosed |
| WO-1993010822-A1 | TECHNETIUM-99 m COMPLEXES WITH N-SUBSTITUTED 3-HYDROXY-4-PYRIDINONES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-06-10 | — | — | WO | disclosed |