Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15688262 | 0.85 | NUDT1 (0.55) | NUDT1ALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL21863368 | 0.80 | L3MBTL1 (0.43) | NUDT1ALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL6937524 | 0.77 | L3MBTL1 (0.41) | NUDT1ALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL2179459 | 0.77 | L3MBTL1 (0.41) | NUDT1ALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL19347319 | 0.77 | NUDT1 (0.50) | NUDT1L3MBTL1TLR7 | |
| SCHEMBL22455542 | 0.77 | NUDT1 (0.50) | NUDT1L3MBTL1TLR7TNKSDYRK1A | |
| SCHEMBL15687846 | 0.76 | L3MBTL1 (0.47) | NUDT1L3MBTL1TNKSADORA2A | |
| Bromide SCHEMBL17873904 | 0.76 | L3MBTL1 (0.40) | NUDT1ALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL21848969 | 0.74 | L3MBTL1 (0.39) | NUDT1L3MBTL1TNKS | |
| SCHEMBL21848955 | 0.74 | L3MBTL1 (0.39) | NUDT1L3MBTL1BACE1BACE2TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116262739-A | Nitrogen-containing aryl derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| WO-2017153527-A1 | NOVEL INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE GAMMA | ASTRAZENECA AB (SE) | 2017-09-14 | — | — | WO | disclosed |
| WO-2014072881-A1 | HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS | PFIZER INC. (US) | 2014-05-15 | — | — | WO | disclosed |
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |