Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380731 | 0.83 | ERCC5 (0.56) | MAPTMEN1KMT2AERCC5FEN1 | |
| SCHEMBL4941615 | 0.82 | MAPT (0.49) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL395494 | 0.76 | MAPT (0.56) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL135637 | 0.75 | MAPT (0.56) | MAPTMEN1KMT2AERCC5FEN1 | |
| SCHEMBL30440405 | 0.73 | MAPT (0.48) | MAPTMEN1KMT2AERCC5FEN1 | |
| SCHEMBL2089796 | 0.73 | MAPT (0.49) | MAPTMEN1KMT2AERCC5FEN1 | |
| SCHEMBL16253911 | 0.73 | MAPT (0.48) | MAPTMEN1KMT2AERCC5FEN1 | |
| SCHEMBL2409184 | 0.72 | TSHR (0.63) | MAPTMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL28056881 | 0.72 | ALDH1A1 (0.43) | MEN1KMT2AERCC5FEN1CYP1A2 | |
| SCHEMBL30991215 | 0.71 | TSHR (0.41) | MEN1KMT2ATSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492906-A | ANTIASTHMATICS, ANTIALLERGENS, GASTROINTESTINAL PROTECTORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5049559-A | Thieno-triazolo-diazepine derivatives useful as anti-ischemic agents | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1991-09-17 | — | — | US | disclosed |