Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081499 | 1.00 | HTR1A (0.48) | HTR1ADRD2 | |
| SCHEMBL9081501 | 1.00 | HTR1A (0.48) | HTR1ADRD2 | |
| SCHEMBL16635504 | 0.93 | HTR1A (0.45) | HTR1ADRD2 | |
| SCHEMBL9964006 | 0.83 | ADRA1A (0.51) | DRD2 | |
| SCHEMBL15139456 | 0.83 | ADRA1A (0.51) | DRD2 | |
| SCHEMBL1950428 | 0.83 | ADRA1A (0.51) | DRD2 | |
| SCHEMBL1950426 | 0.83 | ADRA1A (0.51) | DRD2 | |
| SCHEMBL15139403 | 0.80 | DRD2 (0.61) | HTR1ADRD2 | |
| SCHEMBL1951790 | 0.80 | DRD2 (0.61) | HTR1ADRD2 | |
| SCHEMBL1951789 | 0.80 | DRD2 (0.61) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486611-A | CENTRAL NERVOUS SYSTEM | THE UPJOHN COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0586525-A1 | CARBOXAMIDO-(1,2N)-CARBOCYCLIC-2-AMINOTETRALIN DERIVATIVES. | UPJOHN CO (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992020655-A1 | CARBOXAMIDO-(1,2N)-CARBOCYCLIC-2-AMINOTETRALIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1992-11-26 | — | — | WO | disclosed |