Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081533 | 0.91 | ALDH1A1 (0.54) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL9080504 | 0.85 | LPAR1 (0.50) | KDM4EALDH1A1LMNALPAR1LPAR5 | |
| SCHEMBL9079913 | 0.84 | TSHR (0.55) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL9081250 | 0.84 | TSHR (0.55) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL9080159 | 0.83 | ALDH1A1 (0.61) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL9081725 | 0.82 | ALDH1A1 (0.59) | KDM4EALDH1A1LMNALPAR1LPAR5 | |
| SCHEMBL9081813 | 0.81 | PTGES (0.48) | KDM4EALDH1A1LMNAHPGDGAA | |
| SCHEMBL9081175 | 0.81 | LPAR1 (0.55) | KDM4EALDH1A1LMNALPAR1LPAR5 | |
| SCHEMBL9082393 | 0.81 | PTGES (0.52) | KDM4EALDH1A1LMNALPAR1LPAR5 | |
| SCHEMBL9080869 | 0.80 | TSHR (0.53) | KDM4EALDH1A1LMNAHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |