Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9082393 | 0.86 | PTGES (0.52) | PTGESALDH1A1NPSR1TDP1LPAR1 | |
| SCHEMBL9081318 | 0.85 | TDP1 (0.55) | PTGESTDP1LPAR1LPAR5TSHR | |
| SCHEMBL9081533 | 0.81 | ALDH1A1 (0.54) | PTGESTRPV1ALDH1A1NPSR1LPAR1 | |
| SCHEMBL9081514 | 0.81 | KDM4E (0.66) | PTGESALDH1A1LPAR1LPAR5KDM4E | |
| SCHEMBL9082264 | 0.77 | ALDH1A1 (0.52) | PTGESTRPV1ALDH1A1NPSR1TDP1 | |
| SCHEMBL9080869 | 0.77 | TSHR (0.53) | PTGESALDH1A1NPSR1TDP1KDM4E | |
| SCHEMBL9081808 | 0.76 | TSPO (0.46) | ALDH1A1KDM4EGAAHPGDNR3C1 | |
| SCHEMBL9081725 | 0.76 | ALDH1A1 (0.59) | PTGESALDH1A1NPSR1LPAR1LPAR5 | |
| SCHEMBL9080051 | 0.75 | ABCC1 (0.51) | PTGESTRPV1ALDH1A1NPSR1ABCC1 | |
| SCHEMBL9082169 | 0.74 | TSHR (0.48) | PTGESALDH1A1NPSR1LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |