SCHEMBL908266

SCHEMBL908266

Cc1ccc(O)c(-n2nccn2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.61
NPC1 O15118 3/20 0.61
RAB9A P51151 2/20 0.61
TRPA1 O75762 2/20 0.46
TP53 P04637 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
ALOX15 P16050 2/20 0.42
HSD17B10 Q99714 2/20 0.42
ALDH1A1 P00352 1/20 0.42
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
ALOX12 P18054 1/20 0.41
CSNK2A1 P68400 1/20 0.38
HCRTR2 O43614 6/20 0.37
HCRTR1 O43613 5/20 0.37
AMY1A P0DUB6 1/20 0.36
IDO1 P14902 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27479321 0.79 LMNA (0.38) LMNANPC1RAB9AALOX15HSD17B10
SCHEMBL14850914 0.79 HSD17B10 (0.47) LMNANPC1RAB9ATDP1HSD17B10
SCHEMBL28530940 0.76 MEN1 (0.43) LMNANPC1RAB9ATDP1ALOX15
SCHEMBL31716870 0.76 NPC1 (0.36) LMNANPC1RAB9AHSD17B10HCRTR2
SCHEMBL20551340 0.76 SMN1; SMN2 (0.46) LMNANPC1RAB9ATP53TDP1
SCHEMBL20551535 0.76 NPC1 (0.36) LMNANPC1RAB9AHSD17B10HCRTR2
SCHEMBL28533584 0.76 IDO1 (0.54) LMNANPC1RAB9ATDP1ALOX15
SCHEMBL3297579 0.76 NPC1 (0.81) LMNANPC1RAB9ATRPA1TP53
Drometrizole SCHEMBL2548258 0.76 NPC1 (1.00) LMNANPC1RAB9ATRPA1TDP1
Drometrizole SCHEMBL15616 0.76 NPC1 (1.00) LMNANPC1RAB9ATRPA1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230418125-A9 Novel Electrochromic Materials, Devices And Applications Of The Same AGRAWAL ANOOP (US) 2023-12-28 US disclosed
US-20220260882-A1 Novel Electrochromic Materials, Devices And Applications Of The Same AGRAWAL ANOOP (US) 2022-08-18 US disclosed
CN-108842932-B High-adhesion polyolefin anti-adhesion film and preparation method thereof 江苏优珀斯材料科技有限公司 2021-03-19 CN disclosed
US-9030724-B2 Flexible and printable electrooptic devices CHROMERA, INC. (US) 2015-05-12 US disclosed
US-8610992-B2 Variable transmission window DONNELLY CORPORATION (US) 2013-12-17 US disclosed
US-8559093-B2 Electrochromic mirror reflective element for vehicular rearview mirror assembly DONNELLY CORPORATION (US) 2013-10-15 US disclosed
US-8511841-B2 Vehicular blind spot indicator mirror DONNELLY CORPORATION (US) 2013-08-20 US disclosed
US-20130063802-A1 VARIABLE TRANSMISSION WINDOW DONNELLY CORPORATION (US) 2013-03-14 US disclosed
US-8294975-B2 Automotive rearview mirror assembly DONNELLY CORPORATION (US) 2012-10-23 US disclosed
US-20120206790-A1 ELECTROCHROMIC MIRROR REFLECTIVE ELEMENT FOR VEHICULAR REARVIEW MIRROR ASSEMBLY DONNELLY CORPORATION (US) 2012-08-16 US disclosed
US-6154306-A Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2000-11-28 US disclosed
EP-0612826-B1 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processing for making such solid films and devices DONNELLY CORP (US) 2000-10-04 EP disclosed
EP-1004649-A2 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2000-05-31 EP disclosed
EP-0975709-A1 ELECTROCHROMIC POLYMERIC SOLID FILMS, MANUFACTURING ELECTROCHROMIC DEVICES USING SUCH SOLID FILMS, AND PROCESSES FOR MAKING SUCH SOLID FILMS AND DEVICES DONNELLY CORPORATION (US) 2000-02-02 EP disclosed
US-6000814-A Vehicular component assembly with hard coated element DONNELLY CORPORATION (US) 1999-12-14 US disclosed
US-6002511-A Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 1999-12-14 US disclosed
US-5910854-A FOR USE AS AN ARCHITECTURAL OR VEHICULAR GLAZING DONNELLY CORPORATION (US) 1999-06-08 US disclosed
EP-0892209-A2 Vehicular component assembly with hard coated element DONNELLY CORPORATION (US) 1999-01-20 EP disclosed
WO-1998042796-A1 ELECTROCHROMIC POLYMERIC SOLID FILMS, MANUFACTURING ELECTROCHROMIC DEVICES USING SUCH SOLID FILMS, AND PROCESSES FOR MAKING SUCH SOLID FILMS AND DEVICES DONNELLY CORPORATION (US) 1998-10-01 WO disclosed
EP-0612826-A1 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processing for making such solid films and devices DONNELLY CORPORATION (US) 1994-08-31 EP disclosed